Characteristics of printing company workers newly diagnosed with occupational cholangiocarcinoma
نویسندگان
چکیده
منابع مشابه
Two offset printing workers with cholangiocarcinoma.
OBJECTIVES Previously, the author reported a cluster of 11 cholangiocarcinoma cases exposed to 1,2-dichloropropane (1,2-DCP) and/or dichloromethane (DCM) in an offset proof-printing company. Before that report, the association between the two chemicals and cholangiocarcinoma had not been known. The current study describes two cholangiocarcinoma patients exposed to 1,2-DCP or DCM in different of...
متن کاملDifferent carcinogenic process in cholangiocarcinoma cases epidemically developing among workers of a printing company in Japan.
Recently, cholangiocarcinoma has epidemically developed among young adult workers of a printing company in Japan. Exposure to organic solvents including 1,2-dichloropropane and/or dichloromethane is supposed to be associated with the carcinoma development. The metabolism of dichloromethane proceeds through a Theta-class glutathione S-transferase (GST) T1-1-catalyzed pathway, where its reactive ...
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Cholangiocarcinoma is a relatively rare cancer, but its incidence is increasing worldwide. Although several risk factors have been suggested, the etiology and pathogenesis of the majority of cholangiocarcinomas remain unclear. Recently, a high incidence of early-onset cholangiocarcinoma was reported among the workers of a printing company in Osaka, Japan. These workers underwent high exposure t...
متن کاملChemical exposure levels in printing workers with cholangiocarcinoma (second report).
OBJECTIVE In several Japanese printing plants, printing workers have suffered from cholangiocarcinoma. 1,2-dichloropropane (1,2-DCP) is considered to be a causative agent, and whether or not other chemicals also contribute to the development of this disease has not been conclusively determined. This study aimed to identify the chemicals used by seven printing workers who developed cholangiocarc...
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Results Among 738 patients with tuberculosis who were admitted during January 2011 and December 2013, 60 were newly diagnosed. Of these, 35 (58.3%) patients had respiratory failure. When comparing those who had respiratory failure (RF) and those who did not (no RF), there was no significant difference in age (RF 47.3 ± 16.9 VS no RF 44.5 ± 15.8, P = 0.51), male sex (71.4% VS 68.0%, P = 0.76), B...
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ژورنال
عنوان ژورنال: Journal of Hepato-Biliary-Pancreatic Sciences
سال: 2014
ISSN: 1868-6974
DOI: 10.1002/jhbp.137